Peptide Stability: Storage & Handling Guidelines

At Paragon Peptides, we use Peptide Stability: Storage & Handling Guidelines

1. Long-Term Storage (Lyophilized) In their freeze-dried (lyophilized) state, peptides like Retatrutide are relatively stable. However, for long-term preservation exceeding 30 days, vials should be stored at -20°C. For storage exceeding one year, -80°C is recommended to completely arrest molecular degradation.

2. Short-Term Storage & Reconstitution If the compound will be used within 1–4 weeks, storage at standard refrigeration temperatures (4°C) is acceptable. -Light Sensitivity: Peptides should always be stored in the dark. Our amber-glass or shielded vials help, but keeping them in an opaque container is best. -Moisture Control: Always allow a vial to reach room temperature before opening or reconstituting to prevent condensation from forming inside the vial.

3. Handling Reconstituted Peptides Once a peptide is dissolved in a solvent like Bacteriostatic Water, it becomes significantly more fragile. -Temperature: Reconstituted peptides must be stored at 4°C. They should never be re-frozen, as the formation of ice crystals can shear the delicate peptide bonds. -Mechanical Stress: Do not shake the vial. When adding solvent, let it run down the side of the glass and gently swirl. Aggressive agitation can cause "denaturation," where the peptide loses its 3D shape.

Shelf-Life Summary Table

• Lyophilized (Powder) Room Temp 2–4 Weeks
• Lyophilized (Powder) 4°C (Fridge) 6–24 Months
• Lyophilized (Powder) 4°C (Fridge) 6–24 Months
• Reconstituted (Liquid) 4°C (Fridge) 7–30 Days (Peptide dependent)